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Clinical Features of Oromandibular Dystonia

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°­½Å¿õ, ÃÖÈñÈÆ, ±è±â¼®, ±è¹ÌÀº,
¼Ò¼Ó »ó¼¼Á¤º¸
°­½Å¿õ ( Kang Shin-Woong ) - ´Ü±¹´ëÇб³ Ä¡°ú´ëÇÐ ±¸°­³»°úÇб³½Ç
ÃÖÈñÈÆ ( Choi Hee-Hun ) - ´Ü±¹´ëÇб³ Ä¡°ú´ëÇÐ ±¸°­³»°úÇб³½Ç
±è±â¼® ( Kim Ki-Suk ) - ´Ü±¹´ëÇб³ Ä¡°ú´ëÇÐ ±¸°­³»°úÇб³½Ç
±è¹ÌÀº ( Kim Mee-Eun ) - ´Ü±¹´ëÇб³ Ä¡°ú´ëÇÐ ±¸°­³»°úÇб³½Ç

Abstract

ÇϾǿÀÌ»óÁõ(oromandibular dystonia, OMD)Àº ÅÎÀ̳ª ±¸°­Á¶Á÷ÀÇ ¹Ýº¹Àû, ºÒ¼öÀÇÀû, ºñÁ¤»óÀûÀÎ ¿òÁ÷ÀÓÀ¸·Î Á¤ÀǵǸç ÀúÀÛ±â´É°ú ±³ÇÕ¿¡ ¹®Á¦¸¦ ÃÊ·¡ÇÏ¿© Ä¡°úÄ¡·á¸¦ ¾î·Æ°Ô ÇÏ°í º¸Ã¶¹°ÀÇ À¯Áö°ï¶õÀ» ¾ß±âÇÒ »Ó ¾Æ´Ï¶ó ÀæÀº ±¸°­ ¿¬Á¶Á÷ ¼Õ»óÀ̳ª ¸¸¼º ¾È¸éÅëÁõÀÇ ¿øÀÎÀÌ µÇ±âµµ ÇϹǷΠġ°úÀÇ»çÀÇ °ü½ÉÀÌ ÇÊ¿äÇÑ ÁúȯÀÌ´Ù. º» ¿¬±¸´Â ´Ü±¹´ëÇб³ Ä¡°ú´ëÇÐ ºÎ¼ÓÄ¡°úº´¿ø ±¸°­³»°ú¿¡ ³»¿øÇÏ¿© OMD·Î Áø´ÜµÇ¾î Ä¡·á¸¦ ¹ÞÀº ȯÀÚµéÀÇ º´·Â±â·ÏºÎ»óÀÇ °ü·Ã Ç׸ñÀ» Á¶»çÇÏ¿© OMD ȯÀÚµéÀÇ ÀÓ»óÀû Ư¡°ú Ä¡·á À¯ÇüÀ» ºÐ¼®ÇÏ¿´´Ù.
2007³â 8¿ùºÎÅÍ 2010³â 4¿ù±îÁö ´Ü±¹Ä¡´ë ºÎ¼Óº´¿ø ±¸°­³»°ú¿¡ ³»¿øÇÑ 78¸íÀÇ OMD ȯÀÚ´Â Æò±Õ 72¼¼ÀÇ °í·ÉÀ̾úÀ¸¸ç ¿©ÀÚ°¡ ³²ÀÚ¿¡ ºñÇØ 3.6¹è ¸¹¾Ò°í, Æò±Õ 10°³¿ù ÀÌ»óÀÇ ºñ±³Àû ±ä º´·Â±â°£À» º¸¿´´Ù. ³»¿øÇÑ OMD ȯÀÚÀÇ °¡Àå ÈçÇÑ ÁÖ¼Ò´Â ÅÎÀÇ ÅëÁõÀ̾úÀ¸¸ç ±× ´ÙÀ½À¸·Î ºóµµ°¡ ³ôÀº ÁÖ¼Ò´Â Åΰú ±¸°­Á¶Á÷ÀÇ Á¶Àý ¾È µÇ´Â ¹Ýº¹ÀûÀÎ ¿òÁ÷ÀÓ°ú ±¸°­Á¶Á÷ÀÇ ÅëÁõÀ̾ú´Ù(p=0.000). OMD À¯ÇüÀº Æ䱸Çü(jaw-closing dystonia)ÀÌ °¡Àå ¸¹¾Ò°í, Ãø¹æ¿îµ¿Çü(lateral jaw-deviation dystonia)°ú º¹ÇÕÇü(combination dystonia)µµ ¸¹ÀÌ ¹ß»ýÇÏ¿´´Ù(p=0.001). ȯÀÚÀÇ 60% ÀÌ»óÀº OMD ¹ß»ý°ú °ü·ÃÇÏ¿© ¶Ñ·ÇÇÑ ¿øÀÎÀ» ÀÎÁöÇÏÁö ¸øÇßÀ¸³ª ¾à 19%ÀÇ È¯ÀÚµéÀº º¸Ã¶Ä¡·á, ¹ßÄ¡ µîÀÇ Ä¡°úÄ¡·á¿Í °ü·Ã ÀÖ´Ù°í º¸°íÇÏ¿´´Ù(p=0.000). º»¿ø¿¡ ³»¿øÇÑ È¯ÀÚ´Â ¾à¹°Ä¡·á°¡ °¡Àå ¸ÕÀú ½ÃµµµÇ¾ú°í ÁøÁ¤Á¦(clonazepam)°¡ °ÅÀÇ ¸ðµç ȯÀÚ(97%)¿¡¼­ ó¹æµÇ¾ú´Ù.
ÀÌ»óÀÇ °á°ú·Î º¼ ¶§, OMD´Â ¶Ñ·ÇÇÏ°Ô ³ëÀÎ, ƯÈ÷ ¿©¼º¿¡°Ô ¸¹ÀÌ ¹ß»ýÇÏ´Â ÁúȯÀ¸·Î¼­ Åΰú ±¸°­Á¶Á÷ÀÇ ÅëÁõÀ» À¯¹ßÇÏ¸ç °ú¹Ý¼ö ÀÌ»óÀº ¶Ñ·ÇÇÑ ¿øÀÎÀ» ¸ð¸£Áö¸¸ ÀϺΠȯÀÚµéÀº Ä¡°úÄ¡·á ÈÄ¿¡ ÀÚ½ÅÀÇ ¹®Á¦¸¦ óÀ½ ÀÎÁöÇÏ´Â °æÇâÀÌ ÀÖ´Ù. ±×·¯¹Ç·Î Ä¡°úÀÇ»ç´Â ȯÀÚ¸¦ Ä¡·áÇÒ ¶§ OMDÀÇ Á¸À縦 °£°úÇÏÁö ¾Êµµ·Ï °ü½É°ú ÁÖÀǸ¦ ±â¿ïÀÏ ÇÊ¿ä°¡ ÀÖ´Ù.

Oromandibular dystonia (OMD) is a form of focal dystonia that affects the masticatory, facial and lingual muscles in any variety of combinations, which results in repetitive involuntary and possibly painful jaw opening, closing, deviation or a combination of these movements. This study aimed to investigate clinical features and treatment type of OMD patients.
By retrospective chart review, the study was conducted to consecutive OMD patients who visited a department of Oral Medicine and Orofacial Pain Clinic in a university dental hospital during Aug 2007 to Apr 2010.
78 OMD patients were identified with female preponderance (M:F=1:3.6) and a mean age of 72 years. Their mean duration of OMD was about 10 months. The most common chief complaints at the first visit was jaw ache, followed by uncontrolled, repetitive movement of the jaw and/or oral tissues, pain in the oral region(p=0.000). The most common subtype of OMD was lateral jaw-deviation dystonia, followed by combination and jaw-closing dystonia(p=0.001).
While no apparent cause was recognized in over 60% of the OMD patients, peripheral trauma including dental treatment such as prosthetic treatment and extraction was the most frequently reported as precipitating factor(p=0.000). Medication was the 1st line therapy for our patients and anxiolytics such as clonazepam was given to most of them.
Based on the results of this study, OMD is the disease of the elderly, particularly of women and causes orofacial pain and compromises function of orofacial region. Some patients considered dental treatment a precipitating factor. Dentists, therefore, should have knowledge of symptoms and treatment of OMD.

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dystonia;oromandibular dystonia;dental treatment

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